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| Genetic Analyzers |
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| Applied Biosystems equips all of its genetic analyzers with the same proven capillary electrophoresis technology, application-specific software, industry-leading BigDye® Terminator chemistry, and world-class support. Whether you need a single-capillary system for a few reactions a day or a multi-capillary system for a few million, AB has your needs covered. And with AB's value-added upgrade program, you won't lose a beat when you decide to increase your throughput. |
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| SOLiD™: Next Generation System for Ultra High-Throughput Sequencing |
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 | One tube single molecule amplification of DNA using emulsion PCR |
| Ultra High-throughput - Up to 3 gigabases of data per run |
| Extreme accuracy - Each base is interrogated twice during sequencing resulting in data accuracy 5-fold higher than other next generation systems |
| Broad application flexibility - high-throughput resequencing, whole genome resequencing, tag based gene expression applications, copy number analysis and small RNA discovery |
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| The Applied Biosystems SOLiD™ System is a revolutionary genetic analysis platform that enables massively parallel sequencing of clonally amplified DNA fragments linked to magnetic beads. The sequencing methodology is based on sequential ligation with dye-labeled oligonucleotides. Sequencing by ligation offers higher accuracy and greater throughput. |
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| Technology |
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| The SOLiD™ System is based on Sequencing by Ligation. In this method, the DNA sequence is generated by measuring the serial ligation of an oligonucleotide by ligase. All fluorescently labeled oligonucleotide probes are present simultaneously and compete for incorporation. After each ligation, the fluorescence signal is measured and then cleaved before another round of ligation takes place. Use of a reset phase allows a reduction in noise and a capping step prevents dephasing. |
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| Applied Biosystems 3130 Genetic Analyzer |
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A flexible solution that provides sophisticated automation and superior performance, at acquisition and operating costs tailored to a growing research lab. Upgradable to 16 capillaries whenever you are ready. |
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| Applied Biosystems 3130xl Genetic Analyzer |
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A Offering 16-capillary throughput, advanced automation capabilities and superior performance, this system is ideal for medium-throughput laboratories that need streamlined set-up and 24-hour unattended operation. |
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| Applied Biosystems 3730 DNA Analyzer |
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High-throughput 48-capillary analyzer dramatically increases productivity, while providing application flexibility and significantly lower project costs. Easily upgradable to 96 capillaries. |
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| Applied Biosystems 3730xl DNA Analyzer |
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Unparalleled market leader for high throughput genetic analysis, providing ever increasing application support, while offering reliable, round-the-clock operation and lower project costs. |
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| Click here for more information |
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